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As the workbook is being saved, the “Macros Disabled” warning will briefly appear. This is normal and intended.  Option B workbooks are saved  with the the red “Macros are disabled” warning message visible in order to ensure that it is visible if you re-open the workbook with macros disabled

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When an Option B workbook is opened, a macro runs that reads some identity information from the registration Registration form and hides the red “Macros are disabled” warning in the header area of the spreadsheet.